Aluminum Maltolate-Induced Toxicity in NT2 Cells Occurs Through Apoptosis and Includes Cytochrome c Release
نویسندگان
چکیده
منابع مشابه
Aluminum maltolate-induced toxicity in NT2 cells occurs through apoptosis and includes cytochrome c release.
Aluminum (Al) compounds are neurotoxic and have been shown to induce experimental neurodegeneration although the mechanism of this effect is unclear. In order to study this neurotoxic effect of Al, we have developed an in vitro model system using Al maltolate and human NT2 cells. Al maltolate at 500 microM caused significant cell death with a 24-h incubation and this toxicity was even more evid...
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ژورنال
عنوان ژورنال: NeuroToxicology
سال: 2004
ISSN: 0161-813X
DOI: 10.1016/j.neuro.2003.12.004